Blog

What is the meaning of piknosis?

What is pyknosis and what are its characteristics?

  • Morphological characteristics of pyknosis and other forms of nuclear destruction Pyknosis, or karyopyknosis, is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis. It is followed by karyorrhexis, or fragmentation of the nucleus.

What is pyknosis and karyorrhexis?

  • It is followed by karyorrhexis, or fragmentation of the nucleus. Pyknosis (from Greek pyknono meaning "to thicken up, to close or to condense") is also observed in the maturation of erythrocytes (a red blood cell) and the neutrophil (a type of white blood cell).

What happens to the nucleus during pyknosis?

  • With pyknosis, the nucleus becomes dense and compact and begins to fragment (karyorrhexis) resulting in spheres of dark-staining nuclear chromatin. Therefore, pyknotic cells have an intact cytoplasmic membrane with one or more, variably sized, dense, round, dark nuclear fragments.

image-What is the meaning of piknosis?
image-What is the meaning of piknosis?
Share this Post: